Current State of Tularemia Immunodiagnostics

Tularemia: current diagnosis and treatment options.

Tularemia is an infection caused by Francisella tularensis with a worldwide distribution and diverse clinical manifestations. Limitations in both culture and serologic testing have led to substantial research into new diagnostic techniques and their clinical application, with PCR testing as the best example. This review focuses on the utility of culture, PCR and serologic testing for tularemia....

Current status of vaccine development for tularemia preparedness

Tularemia is a high-risk infectious disease caused by Gram-negative bacterium Francisella tularensis. Due to its high fatality at very low colony-forming units (less than 10), F. tularensis is considered as a powerful potential bioterrorism agent. Vaccine could be the most efficient way to prevent the citizen from infection of F. tularensis when the bioterrorism happens, but officially approved...

Immunodiagnostics in aquaculture

Introduction Fish in culture are susceptible to a wide range of bacterial, viral, parasitic and fungal infections (Austin & Austin, 1993) and losses through disease currently make a significant impact on the quality and volume of fish produced in Europe. Disease control is therefore a vital component of successful aquaculture. Rapid detection and identification of pathogens is necessary for eff...

Immunodiagnostics for Leprosy

Prospects of Nanotechnology in Clinical Immunodiagnostics

Nanostructured materials are promising compounds that offer new opportunities as sensing platforms for the detection of biomolecules. Having micrometer-scale length and nanometer-scale diameters, nanomaterials can be manipulated with current nanofabrication methods, as well as self-assembly techniques, to fabricate nanoscale bio-sensing devices. Nanostructured materials possess extraordinary ph...